Contact Us:
STEMM
PO Box 871
Sioux City, IA 51102
Ph: 712-258-8282
Fax: 712-226-2687
mbechler@cableone.net
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SKELETAL FLUOROSIS
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In
Tanzania, and other countries of East Africa, Skeletal
Fluorosis is caused by drinking water from borehole wells
that have extremely high concentrations of fluoride.
Fluoride is an extremely unstable isotope of fluorine,
which has an atomic number of 9. Fluoride seeks electrons
to complete its outer valance, and in the mammalian body,
calcium or phosphorous often supply those electrons.
When this happens, the remaining isotope of calcium or
phosphorous can not form its usual crystalline matrix,
in bone tissue. Hence, the disfiguring
conditions of Skeletal Fluorosis. Fluoride also inhibits
the body’s ability to utilize vitamin D, which
leads to rickets like softness of the bone called osteomalacia.
Finally, since fluoride has changed the free calcium
in the body to a form that is not recognized, the body
uploads the calcium it needs from bones, and further
weakens the bony tissues.
Skeletal
Fluorosis can take several forms. Dr. Meyer and I try to
concentrate on lower extremity deformities of the femur and tibia.
Quite often the deformities affect the femurs and tibias, bilaterally.
We then have to make decisions concerning how well the
child can tolerate the procedures. Many times we have to
operate on one leg at the beginning of the mission, and
wait several days to operate on the other leg. This has
to do with the fact that there is no blood bank, and even
if there were, most Tanzanians will not allow the use of
someone else’s blood. This is due, in large part,
to the HIV epidemic in sub-Saharan Africa.
Although
we have not conducted any surgical procedures concerning
them, we have seen some involvement of upper
extremities. Whenever possible, we try to conserve
the few resources that we have in order to have the greatest
impact on the children. If a child can still feed themselves,
drink, and write, we use ours time and resources to help
children who may not be able to walk. |
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Skeletal
Fluorosis: An Annotated Bibliography
Prepared
by Robert K. Thompson - April 2, 2003 |
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Ando, M., Tadano, S., Yamamoto, S., Tamura, K., Asanuma, S.,
Watanabe, T., Kondo,
T., Sakurai, S., Ji, R., Liang, C., Chen, X., Hong, Z., and Cao,
S. (2001). Health effects of fluoride pollution caused by coal
burning. Sci. Total Environ., 271(1-3), 107-116.
Recently a huge
amount of fluoride in coal has been released into indoor
environments by the combustion of coal and fluoride
pollution seems to be increasing in some rural areas in China.
Combustion of coal and coal bricks is the primary source
of gaseous and aerosol fluoride and these forms of fluoride
can
easily enter exposed food products and the human respiratory
tract. Major human fluoride exposure was caused by consumption
of fluoride-contaminated food, such as corn, chilies and
potatoes. For each diagnostic syndrome of dental fluorosis,
a log-normal
distribution was observed on the logarithm of urinary fluoride
concentration in students in China. [more]
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