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STEMM
PO Box 871
Sioux City, IA 51102

Ph:   712-258-8282
Fax: 712-226-2687

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SKELETAL FLUOROSIS


 

In Tanzania, and other countries of East Africa, Skeletal Fluorosis is caused by drinking water from borehole wells that have extremely high concentrations of fluoride. Fluoride is an extremely unstable isotope of fluorine, which has an atomic number of 9. Fluoride seeks electrons to complete its outer valance, and in the mammalian body, calcium or phosphorous often supply those electrons. When this happens, the remaining isotope of calcium or phosphorous can not form its usual crystalline matrix, in bone tissue. Hence, the disfiguring conditions of Skeletal Fluorosis. Fluoride also inhibits the body’s ability to utilize vitamin D, which leads to rickets like softness of the bone called osteomalacia. Finally, since fluoride has changed the free calcium in the body to a form that is not recognized, the body uploads the calcium it needs from bones, and further weakens the bony tissues.

Skeletal Fluorosis can take several forms. Dr. Meyer and I try to concentrate on lower extremity deformities of the femur and tibia. Quite often the deformities affect the femurs and tibias, bilaterally. We then have to make decisions concerning how well the child can tolerate the procedures. Many times we have to operate on one leg at the beginning of the mission, and wait several days to operate on the other leg. This has to do with the fact that there is no blood bank, and even if there were, most Tanzanians will not allow the use of someone else’s blood. This is due, in large part, to the HIV epidemic in sub-Saharan Africa.

Although we have not conducted any surgical procedures concerning them, we have seen some involvement of upper extremities. Whenever possible, we try to conserve the few resources that we have in order to have the greatest impact on the children. If a child can still feed themselves, drink, and write, we use ours time and resources to help children who may not be able to walk.

   
Skeletal Fluorosis: An Annotated Bibliography
Prepared by Robert K. Thompson - April 2, 2003
  Ando, M., Tadano, S., Yamamoto, S., Tamura, K., Asanuma, S., Watanabe, T., Kondo,
T., Sakurai, S., Ji, R., Liang, C., Chen, X., Hong, Z., and Cao, S. (2001). Health effects of fluoride pollution caused by coal burning. Sci. Total Environ., 271(1-3), 107-116.

Recently a huge amount of fluoride in coal has been released into indoor environments by the combustion of coal and fluoride pollution seems to be increasing in some rural areas in China. Combustion of coal and coal bricks is the primary source of gaseous and aerosol fluoride and these forms of fluoride can easily enter exposed food products and the human respiratory tract. Major human fluoride exposure was caused by consumption of fluoride-contaminated food, such as corn, chilies and potatoes. For each diagnostic syndrome of dental fluorosis, a log-normal distribution was observed on the logarithm of urinary fluoride concentration in students in China. [more]



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